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1

Effects of different drying–solidification processes on physical properties, volatile fraction, and antioxidant activity of non-centrifugal cane brown sugar

Asikin, Yonathan, Hirose, Naoto, Tamaki, Hajime, Ito, Satoru, Oku, Hirosuke, Wada, Koji

Journal:

Lebensmittel-Wissenschaft und-Technologie / Food Science and Technology

Année:

2015

Langue:

english

Fichier:

PDF, 2.18 MB

english, 2015

2

Development of a liposomal drug delivery system for the treatment of ischemic stroke

Fukuta, Tatsuya, Asai, Tomohiro, Oku, Naoto

Journal:

Drug Delivery System

Année:

2015

Fichier:

PDF, 3.32 MB

2015

3

Molecular Recognition Systems on the Plasma Membrane : Roles of Membrane Lipids.

Shibamoto, Sayumi, Oku, Naoto

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 1.66 MB

english, 1991

4

Evaluating tamsulosin hydrochloride-released microparticles prepared using single-step matrix coating

Atsushi Maeda, Tatsuki Shinoda, Naoki Ito, Keizo Baba, Naoto Oku, Takao Mizumoto

Journal:

International Journal of Pharmaceutics

Année:

2011

Langue:

english

Fichier:

PDF, 533 KB

english, 2011

5

Oral delivery of insulin by using surface coating liposomes: Improvement of stability of insulin in GI tract

Kazunori Iwanaga, Satoshi Ono, Kohji Narioka, Kazuhiro Morimoto, Masawo Kakemi, Shinji Yamashita, Mamoru Nango, Naoto Oku

Journal:

International Journal of Pharmaceutics

Année:

1997

Langue:

english

Fichier:

PDF, 112 KB

english, 1997

6

Delivery of contrast agents for positron emission tomography imaging by liposomes

Journal:

Advanced Drug Delivery Reviews

Année:

1999

Langue:

english

Fichier:

PDF, 436 KB

english, 1999

7

Treatment of stroke with liposomal neuroprotective agents under cerebral ischemia conditions

Fukuta, Tatsuya, Ishii, Takayuki, Asai, Tomohiro, Sato, Akihiko, Kikuchi, Takashi, Shimizu, Kosuke, Minamino, Tetsuo, Oku, Naoto

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Année:

2015

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2015

8

.BETA.-Thujaplicin Zinc Chelate Induces Apoptosis in Mouse High Metastatic Melanoma B16BL6 Cells.

MIYAMOTO, Daisei, ENDO, Naoko, OKU, Naoto, ARIMA, Yaeno, SUZUKI, Takashi, SUZUKI, Yasuo

Journal:

Biological & Pharmaceutical Bulletin

Année:

1998

Fichier:

PDF, 883 KB

1998

9

Chemoprevention of Tumor Metastasis by Liposomal β-Sitosterol Intake

Imanaka, Hiromichi, Koide, Hiroyuki, Shimizu, Kosuke, Asai, Tomohiro, Kinouchi Shimizu, Naomi, Ishikado, Atsushi, Makino, Taketoshi, Oku, Naoto

Journal:

Biological & Pharmaceutical Bulletin

Année:

2008

Langue:

english

Fichier:

PDF, 1018 KB

english, 2008

10

Evaluation of the alternative classification criteria of systemic lupus erythematosus established by Systemic Lupus International Collaborating Clinics (SLICC)

Oku, Kenji, Atsumi, Tatsuya, Akiyama, Yuji, Amano, Hirofumi, Azuma, Naoto, Bohgaki, Toshiyuki, Asanuma, Yu Funakubo, Horita, Tetsuya, Hosoya, Tadashi, Ichinose, Kunihiro, Kato, Masaru, Katsumata, Yasu

Journal:

Modern Rheumatology

Année:

2017

Fichier:

PDF, 959 KB

2017

11

Innovations in Liposomal DDS Technology and Its Application for the Treatment of Various Diseases

Année:

2017

Langue:

english

Fichier:

PDF, 4.92 MB

english, 2017

12

Challenge for oral delivery of middle-molecular drugs: Use of osmolarity-sensitive liposome as a drug carrier in the GI tract

Minami, Keiko, Takazawa, Asuka, Taniguchi, Yuki, Higashino, Haruki, Kataoka, Makoto, Asai, Tomohiro, Oku, Naoto, Yamashita, Shinji

Journal:

Journal of Drug Delivery Science and Technology

Année:

2019

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2019

13

Key determinants of siRNA delivery mediated by unique pH-responsive lipid-based liposomes

Sako, Mariko, Song, Furan, Okamoto, Ayaka, Koide, Hiroyuki, Dewa, Takehisa, Oku, Naoto, Asai, Tomohiro

Journal:

International Journal of Pharmaceutics

Année:

2019

Fichier:

PDF, 1.78 MB

2019

14

Charge-reversible Lipid Derivative: A Novel Type of pH-responsive Lipid for Nanoparticle-mediated siRNA Delivery

Hirai, Yusuke, Saeki, Ryoko, Song, Furan, Koide, Hiroyuki, Fukata, Naofumi, Tomita, Koji, Maeda, Noriyuki, Oku, Naoto, Asai, Tomohiro

Journal:

International Journal of Pharmaceutics

Année:

2020

Fichier:

PDF, 4.39 MB

2020

15

Functional role of sialyl Lewis X and fibronectin-derived RGDS peptide analogue on tumor-cell arrest in lungs followed by extravasation

Ikuo Saiki, Chieko Koike, Aya Obata, Hideki Fujii, Jun Murata, Makoto Kiso, Akira Hasegawa, Hiroyuki Komazawa, Hideo Tsukada, Ichiro Azuma, Shoji Okada, Naoto Oku

Journal:

International Journal of Cancer

Année:

1996

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1996

16

IN VIVO TRAFFICKING OF LONG-CIRCULATING LIPOSOMES IN TUMOUR-BEARING MICE DETERMINED BY POSITRON EMISSION TOMOGRAPHY

Naoto Oku, Yoshihiro Tokudome, Hideo Tsukada, Tsuyoshi Kosugi, Yukihiro Namba, Shoji Okada

Journal:

Biopharmaceutics & Drug Disposition

Année:

1996

Langue:

english

Fichier:

PDF, 394 KB

english, 1996

17

Usefulness of positron emission tomographic visualization for examination of in vivo susceptibility to metastasis

Hironori Kikkawa, Hideo Tsukada, Naoto Oku

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 329 KB

english, 2000

18

Manganese concentration in mouse brain after intravenous injection

Naoki Sotogaku, Naoto Oku, Atsushi Takeda

Journal:

Journal of Neuroscience Research

Année:

2000

Langue:

english

Fichier:

PDF, 206 KB

english, 2000

19

Zinc homeostasis in the brain of adult rats fed zinc-deficient diet

Atsushi Takeda, Akira Minami, Sachiyo Takefuta, Minori Tochigi, Naoto Oku

Journal:

Journal of Neuroscience Research

Année:

2001

Langue:

english

Fichier:

PDF, 265 KB

english, 2001

20

ChemInform Abstract: Elucidation of Accelerated Blood Clearance Phenomenon Caused by Repeat Injection of PEGylated Nanocarriers.

Hiroyuki Koide, Tomohiro Asai, Kentaro Hatanaka, Kosuke Shimizu, Masayuki Yokoyama, Tatsuhiro Ishida, Hiroshi Kiwada, Naoto Oku

Journal:

Année:

2010

Fichier:

PDF, 13 KB

2010

21

Induction of intensive tumor suppression by antiangiogenic photodynamic therapy using polycation-modified liposomal photosensitizer

Yoshito Takeuchi, Kohta Kurohane, Kanae Ichikawa, Sei Yonezawa, Mamoru Nango, Naoto Oku

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 221 KB

english, 2003

22

Anti-neovascular therapy by liposomal drug targeted to membrane type-1 matrix metalloproteinase

Masami Kondo, Tomohiro Asai, Yasufumi Katanasaka, Yasuyuki Sadzuka, Hideo Tsukada, Koichi Ogino, Takao Taki, Kazuhiko Baba, Naoto Oku

Journal:

International Journal of Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 523 KB

english, 2004

23

Cancer antineovascular therapy with liposome drug delivery systems targeted to BiP/GRP78

Yasufumi Katanasaka, Takayuki Ishii, Tomohiro Asai, Hirotaka Naitou, Noriyuki Maeda, Fumiaki Koizumi, Shinichi Miyagawa, Norio Ohashi, Naoto Oku

Journal:

International Journal of Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2010

24

Therapeutic effect of adriamycin encapsulated in long-circulating liposomes on meth-a-sarcoma-bearing mice

Naoto Oku, Kanako Doi, Yukihiro Namba, Shoji Okada

Journal:

International Journal of Cancer

Année:

1994

Langue:

english

Fichier:

PDF, 563 KB

english, 1994

25

Possible role of prostaglandins as negative regulators in growth stimulation by tumor necrosis factor and epidermal growth factor in human fibroblasts

Takamitsu Hori, Satoshi Kashiyama, Makio Hayakawa, Sayumi Shibamoto, Masafumi Tsujimoto, Naoto Oku, Fumiaki Ito

Journal:

Journal of Cellular Physiology

Année:

1989

Langue:

english

Fichier:

PDF, 584 KB

english, 1989

26

Release of glutamate and GABA in the hippocampus under zinc deficiency

Atsushi Takeda, Maki Hirate, Haruna Tamano, Naoto Oku

Journal:

Journal of Neuroscience Research

Année:

2003

Langue:

english

Fichier:

PDF, 263 KB

english, 2003

27

Differential effects of zinc on glutamatergic and GABAergic neurotransmitter systems in the hippocampus

Atsushi Takeda, Akira Minami, Yumiko Seki, Naoto Oku

Journal:

Journal of Neuroscience Research

Année:

2004

Langue:

english

Fichier:

PDF, 197 KB

english, 2004

28

Inhibition of presynaptic activity by zinc released from mossy fiber terminals during tetanic stimulation

Akira Minami, Naomi Sakurada, Sayuri Fuke, Kazuya Kikuchi, Tetsuo Nagano, Naoto Oku, Atsushi Takeda

Journal:

Journal of Neuroscience Research

Année:

2006

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2006

29

Role of zinc influx via AMPA/kainate receptor activation in metabotropic glutamate receptor-mediated calcium release

Atsushi Takeda, Sayuri Fuke, Akira Minami, Naoto Oku

Journal:

Journal of Neuroscience Research

Année:

2007

Langue:

english

Fichier:

PDF, 332 KB

english, 2007

30

Negative modulation of presynaptic activity by zinc released from schaffer collaterals

Atsushi Takeda, Sayuri Fuke, Wataru Tsutsumi, Naoto Oku

Journal:

Journal of Neuroscience Research

Année:

2007

Langue:

english

Fichier:

PDF, 503 KB

english, 2007

31

Attenuation of hippocampal mossy fiber long-term potentiation by low micromolar concentrations of zinc

Atsushi Takeda, Shingo Kanno, Naomi Sakurada, Masaki Ando, Naoto Oku

Journal:

Journal of Neuroscience Research

Année:

2008

Langue:

english

Fichier:

PDF, 204 KB

english, 2008

32

Involvement of N-methyl-D-aspartate receptor subunits in zinc-mediated modification of CA1 long-term potentiation in the developing hippocampus

Atsushi Takeda, Kosuke Itagaki, Masaki Ando, Naoto Oku

Journal:

Journal of Neuroscience Research

Année:

2012

Langue:

english

Fichier:

PDF, 547 KB

english, 2012

33

Inhibitory function of zinc against excitation of hippocampal glutamatergic neurons

Atsushi Takeda, Akira Minami, Yumiko Seki, Naoto Oku

Journal:

Epilepsy Research

Année:

2003

Langue:

english

Fichier:

PDF, 199 KB

english, 2003

34

Involvement of unusual glutamate release in kainate-induced seizures in zinc-deficient adult rats

Atsushi Takeda, Haruna Tamano, Naoto Oku

Journal:

Epilepsy Research

Année:

2005

Langue:

english

Fichier:

PDF, 224 KB

english, 2005

35

Region-specific loss of zinc in the brain in pentylentetrazole-induced seizures and seizure susceptibility in zinc deficiency

Atsushi Takeda, Hiromasa Itoh, Maki Hirate, Naoto Oku

Journal:

Epilepsy Research

Année:

2006

Langue:

english

Fichier:

PDF, 2.43 MB

english, 2006

36

Abnormal Ca2+ mobilization in hippocampal slices of epileptic animals fed a zinc-deficient diet

Atsushi Takeda, Hiromasa Itoh, Akito Nagayoshi, Naoto Oku

Journal:

Epilepsy Research

Année:

2009

Langue:

english

Fichier:

PDF, 810 KB

english, 2009

37

Particle size-dependent triggering of accelerated blood clearance phenomenon

Hiroyuki Koide, Tomohiro Asai, Kentaro Hatanaka, Takeo Urakami, Takayuki Ishii, Eriya Kenjo, Masamichi Nishihara, Masayuki Yokoyama, Tatsuhiro Ishida, Hiroshi Kiwada, Naoto Oku

Journal:

International Journal of Pharmaceutics

Année:

2008

Langue:

english

Fichier:

PDF, 274 KB

english, 2008

38

T cell-independent B cell response is responsible for ABC phenomenon induced by repeated injection of PEGylated liposomes

Hiroyuki Koide, Tomohiro Asai, Kentaro Hatanaka, Shuji Akai, Takayuki Ishii, Eriya Kenjo, Tatsuhiro Ishida, Hiroshi Kiwada, Hideo Tsukada, Naoto Oku

Journal:

International Journal of Pharmaceutics

Année:

2010

Langue:

english

Fichier:

PDF, 435 KB

english, 2010

39

PET imaging of brain cancer with positron emitter-labeled liposomes

Naoto Oku, Mina Yamashita, Yurie Katayama, Takeo Urakami, Kentaro Hatanaka, Kosuke Shimizu, Tomohiro Asai, Hideo Tsukada, Shuji Akai, Hiroaki Kanazawa

Journal:

International Journal of Pharmaceutics

Année:

2011

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2011

40

Agitation during lipoplex formation improves the gene knockdown effect of siRNA

Jose Mario Barichello, Shinji Kizuki, Tatsuaki Tagami, Tomohiro Asai, Tatsuhiro Ishida, Hiroshi Kikuchi, Naoto Oku, Hiroshi Kiwada

Journal:

International Journal of Pharmaceutics

Année:

2011

Langue:

english

Fichier:

PDF, 723 KB

english, 2011

41

Synthesis of angiogenesis-targeted peptide and hydrophobized polyethylene glycol conjugate

Noriyuki Maeda, Yoshito Takeuchi, Miki Takada, Yukihiro Namba, Naoto Oku

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 153 KB

english, 2004

42

Enhanced excitability of hippocampal mossy fibers and CA3 neurons under dietary zinc deficiency

Atsushi Takeda, Kohei Yamada, Akira Minami, Tetsuo Nagano, Naoto Oku

Journal:

Epilepsy Research

Année:

2005

Langue:

english

Fichier:

PDF, 240 KB

english, 2005

43

Distribution of trace elements in the brain of EL (epilepsy) mice

Maki Hirate, Atsushi Takeda, Haruna Tamano, Shuichi Enomoto, Naoto Oku

Journal:

Epilepsy Research

Année:

2002

Langue:

english

Fichier:

PDF, 340 KB

english, 2002

44

Zinc movement in the brain under kainate-induced seizures

Atsushi Takeda, Maki Hirate, Haruna Tamano, Naoto Oku

Journal:

Epilepsy Research

Année:

2003

Langue:

english

Fichier:

PDF, 248 KB

english, 2003

45

Cancer chemotherapy administered by activated carbon particles and liposomes

Akeo Hagiwara, Toshio Takahashi, Naoto Oku, Shigeru Tsukagoshi

Journal:

Critical Reviews in Oncology/Hematology

Année:

1989

Langue:

english

Fichier:

PDF, 4.03 MB

english, 1989

46

Susceptibility to kainate-induced seizures under dietary zinc deficiency

Atsushi Takeda, Maki Hirate, Haruna Tamano, Daisuke Nisibaba, Naoto Oku

Journal:

Journal of Neurochemistry

Année:

2003

Langue:

english

Fichier:

PDF, 245 KB

english, 2003

47

Identification of melanoma-specific serological markers using proteomic analyses

Masako Takikawa, Yasuto Akiyama, Tadashi Ashizawa, Akifumi Yamamoto, Naoya Yamazaki, Yoshio Kiyohara, Naoto Oku, Ken Yamaguchi

Journal:

PROTEOMICS - Clinical Applications

Année:

2009

Langue:

english

Fichier:

PDF, 562 KB

english, 2009

48

Design of Synthetic Polymer Nanoparticles that Capture and Neutralize a Toxic Peptide

Yu Hoshino, Takeo Urakami, Takashi Kodama, Hiroyuki Koide, Naoto Oku, Yoshio Okahata, Kenneth J. Shea

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 474 KB

english, 2009

49

PCR-mediated Detection ofXanthomonas oryzaepv.oryzaeby Amplification of the 16S–23S rDNA Spacer Region Sequence

Naoto ADACHI, Takashi OKU

Journal:

Journal of General Plant Pathology

Année:

2000

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2000

50

Liposomalization of hydroxyphenyl fluorescein as a reagent for detecting highly reactive oxygen species

Ikumi Sugiyama, Saki Kojima, Naoto Oku, Yasuyuki Sadzuka

Journal:

Colloid & Polymer Science

Année:

2010

Langue:

english

Fichier:

PDF, 252 KB

english, 2010